Deep Vein Thrombosis - Approximately 600, 000 new cases are diagnosed in the U

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  • 1.Approximately 600,000 new cases are diagnosed in the U.S. each year Thrombus formation in deep veins of legs or thighs Deep Vein Thrombosis Tibial veins, soleal/gastrocnemius veins, popliteal vein femoral vein, deep femoral vein, common femoral vein, iliac veins.
  • 2.Approximately one-third develop pulmonary embolism Deep Vein Thrombosis 15% Death
  • 3.VTE: Epidemiology Untreated Proximal DVT 30-50% risk PE 12-15% mortality Treated DVT <8% risk PE Mortality <2%
  • 4.VTE: Epidemiology Incidence - USA/Europe DVT: 160 per 100,000 Symptomatic non-fatal PE: 20 per 100,000 Fatal PE: 50 per 100,000
  • 5.VTE: Pathophysiology Virchow’s Triad Alterations in blood flow - Venous Stasis Alterations in blood constituents Vascular endothelium damage
  • 6.VTE: Predisposing Factors Principal Risk Factors Immobilization Trauma Surgery Infection Post-partum period Other Factors Age Obesity Malignancy Previous VTE Varicose Veins Dehydration Hormonal Therapy
  • 7.VTE: Signs & Symptoms DVT Asymptomatic Pain/tenderness Erythema Acute swelling Pallor- Phlegmasia Alba Cyanosis-Phlegmasia Cerulea PE Dyspnea & Tachypnea Diaphoresis Hemoptysis Low-grade fever Pleuritic CP Cough Hypotension Coma CXR EKG
  • 8.VTE: Diagnosis Venography – ex-gold standard Duplex Ultrasound Comfortable Inexpensive No risk Good sensitivity and specificity for distal Less sensitive for proximal DVT
  • 9.Arteries and Veins
  • 10.The Superficial Femoral Vein A Potentially Lethal Misnomer Warner P. Bundens, MD; John J. Bergan, MD; Nicholas A. Halasz, MD; Jay Murray, MD; Margaret Drehobl, MD. JAMA. 1995;274:1296-1298 A total of 46 family practitioners and general internists, 95 anatomists, and 85 laboratory directors. Only 24% (11/46) of the respondents would have administered anticoagulants to the patient as described
  • 11.Only 3% (3/95) of anatomists felt the term "superficial femoral vein" was correct, 22% (21/95) felt it was an acceptable alternative, and only 7% (7/95) of anatomists felt the term was preferred for everyday use The term "superficial femoral vein" is used by 93% (79/85) of vascular laboratories in lower limb venous duplex reports. The Superficial Femoral Vein A Potentially Lethal Misnomer Warner P. Bundens, MD; John J. Bergan, MD; Nicholas A. Halasz, MD; Jay Murray, MD; Margaret Drehobl, MD. JAMA. 1995;274:1296-1298
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  • 13.Correct nomenclature The term “superficial femoral vein “ should never be used, because the femoral vein is in fact a deep vein and is not part of the superficial venous system. Confusion arising from use of the inappropriate name has been responsible for many cases of clinical mismanagement and death Management of “superficial femoral vein” thrombosis should be the same as any DVT