1.Tapentadol in the treatment of cancer pain
2. Pain in cancer patients is frequently undermedicated and can have both nociceptive and neuropathic components.
In 40% of cancer patients, pain is rated as moderate or severe.
It has been linked to disruptions in daily activities, sleep, mood, and social interactions.
3.How Tapentadol helps?
Tapentadol was well tolerated and effective in cancer pain patients.
Thus, It can be considered a universal analgesic for the administration of moderate-to-severe cancer pain in opioid-naive and opioid-pretreated patients.
It’s analgesic efficacy may be attributed, at least in part, to its action on neuropathic pain components.
It's lower rate of gastrointestinal adverse effects and overall favorable safety profile compared to other opioid analgesics may be advantageous in cancer patients who frequently experience nausea, vomiting, constipation, or other events that reduce their quality of life.
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